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Combatting HPAI: Key health strategies

A framework for modern data collection techniques serving public health  

High pathogen avian influenza (HPAI), including strains such as H5N1 and H7N9, remains a significant threat to global health. Characterized by high mortality rates, rapid transmission and potential for pandemic outbreaks, HPAI requires robust surveillance, research and coordinated strategies.  

The rising threat of HPAI poses challenges to community health and economic stability. Effective management relies on comprehensive surveillance and data collection to understand the virus's transmission modes, environmental influences, symptomology and genetic traits. Immediate response measures, such as culling infected birds and enforcing biosecurity protocols, are critical. Early detection and a robust public health framework — encompassing precise data collection and international cooperation — remain essential for preventing widespread outbreaks and minimizing the virus's impact.

HPAI cases in the United States from April 2022- August 2024

14

total reported human cases in the U.S.

4 

human cases infected following exposure to dairy cows

3

U.S.states with reported human cases

Source: Centers for Disease Control

Cumulative number of laboratory-confirmed human cases and deaths 2003-2024

 

Australia
Cambodia
China
Lao PDR
Vietnam
Total

Cases

1
69
56
3
129
258

Deaths

0
42
32
2
65
141

Source: World Health Organization

Effective surveillance and data collection are crucial in managing HPAI. Surveillance efforts focus on gathering essential information to monitor and understand the spread of the virus. 

HPAI: Understanding key data elements 

Effectively managing HPAI requires collecting and analyzing key factors that reveal insights into the virus's behavior, helping to inform surveillance efforts and response strategies. 

  • Modes of transmission: Monitoring HPAI is crucial to understand and track its various modes of transmission, which include direct interaction with infected birds, contact with contaminated surfaces or tools, and inhalation of airborne particles carrying the virus.
  • Environmental factors that facilitate transmission: Factors including temperature, humidity, migratory patterns, and the density of populations can all influence the transmission dynamics of the virus.
  • Symptomology: Recording the clinical symptoms observed in infected humans is vital for early detection and diagnosis. This includes noting the severity and progression of symptoms, which can vary depending on the HPAI strain and the host species.
  • Genetic characteristics of HPAI: Analyzing the genetic makeup of HPAI viruses helps in understanding their evolution, mutations and potential changes in virulence or transmissibility. This data is crucial for developing targeted vaccines and treatments, as well as for predicting potential pandemic strains. 

Designing HPAI outbreak response 

Upon detecting HPAI infections, immediate post-infection measures are essential to mitigate spread. These measures include culling infected birds to prevent further transmission, implementing strict biosecurity protocols to minimize risks of contamination, and vaccinating susceptible populations to bolster immunity and reduce the virus's impact on both animal and human health. Swift and decisive action is crucial to containing outbreaks and preventing widespread dissemination. 

The potential for pandemic outbreaks necessitates international cooperation, as the spread of HPAI knows no borders. Thus, the global health community must remain vigilant, ensuring that the tools and strategies are in place to mitigate the impact of HPAI and protect populations from its potentially catastrophic effects. 

A public health framework for HPAI control efforts 

A system to control HPAI is essential for orchestrating comprehensive and effective response strategies. Such a framework should integrate surveillance systems to monitor and analyze spread, elucidate modes of transmission, and identify affected species and Public health officials must prioritize early detection and prevention through robust reporting mechanisms, outbreak linkages, and contact tracing. In our expertise, four critical pillars can foster this strategy: 

  1. Understand modes of transmission: Monitoring HPAI is crucial to understand and track its various modes of transmission, which include direct interaction with infected birds, contact with contaminated surfaces or tools, and inhalation of airborne particles carrying the virus.
  2. Design a surveillance framework: Monitoring helps in collecting important data elements such as affected species, environmental exposures, symptomology, and genetic characteristics of the virus. This data is essential for understanding how the disease spreads and its patterns.
  3. Implement control measures: Effective monitoring facilitates the timely implementation of containment measures, such as culling infected birds, strict biosecurity protocols, and vaccination of susceptible populations.
  4. Early detection and prevention: Early detection through surveillance allows for prompt responses to potential outbreaks. This includes establishing reporting mechanisms, conducting outbreak linkages, contact tracing, and aggregating cases for effective management and prevention of widespread outbreaks.

By designing a coordinated approach among health authorities, researchers and policymakers, this framework can enhance preparedness, mitigate the impact of outbreaks, and safeguard global public health. 

The growing power of disease surveillance and outbreak management systems 

For diseases like HPAI, automated surveillance and outbreak management solutions provide secure and efficient tracking, management and reporting of health status across individuals, communities and countries. These tools effectively monitor and address communicable diseases and exposure risks. 

Conduent’s Maven® platform is designed to track, manage and report on the health status of individuals, communities, and countries, including those exposed to communicable diseases securely and efficiently. 

Maven provides government agencies with a platform to enhance healthcare outcomes through actionable insights and case management processes.  

Box: How Maven helps monitor and track HPAI  
Maven enables timely, precise collaboration between healthcare organizations and public health organizations, aiding in disease containment, contact tracing and public health analysis. 

  • State and local health agencies can systematically collect and transmit real-time reports to the CDC through automated mechanisms. 
  • Features the largest global user base sharing best practices in clinical and business processes.
  • Secured hosting available on Amazon Web Services (AWS), Azure, or Conduent Cloud.
  • Facilitates automation in contact tracing, reporting, and management.
  • Highly configurable, enabling user modifications without the need for extensive source code alterations.
  • Provides a fully managed service with ongoing updates and patch management.


Explore why Maven is the preferred platform for public health agencies globally. Visit our website to learn more about how we can support your efforts in monitoring and tracking HPAI and connect with our experts for personalized assistance. 
https://www.conduent.com/government-solutions/government-healthcare-solutions/disease-surveillance-outbreak-management-system/ 

About the Author

Alycia McNutt is an epidemiologist with Conduent’s Public Health Solutions. She channels her passion for data and analytics to provide enhancements to Conduent’s Maven Disease Surveillance and Outbreak Management System. With a background in bacterial genomics and several publications including outbreak detection using WGS in multi-state outbreaks, Alycia sheds light on the intricate web of microbial life and its impact on human health.

Profile Photo of Alycia McNutt
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